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May 31, 2009

The prevalence cervical facet arthrosis

Filed under: Arthritis, Neck Pain — Administrator @ 7:22 pm

The prevalence cervical facet arthrosis: an osseous study in a cadveric population

From: Spine J. 2009 May 26. [Epub ahead of print]

Cervical facet arthrosis has been implicated as a cause for neck pain, radiculopathy, occipital headache, and ear pain. The objective of this study was to examine the occurrence of facet arthrosis in the cervical spine. This study examined cadaveric specimens from the Hamann Todd Collection. Four hundred sixty-five skeletally mature human cervical spines from the Hamann Todd Collection in the Cleveland Museum of Natural History were obtained for analysis. The authors analyzed the facets for arthrosis. We graded no arthrosis as Grade 0. Facets with peripheral osteophytic reaction, but with no lateral mass distortion were graded as Grade 1. Facets with peripheral osteophytic reaction and lateral mass distortion were graded as Grade 2. Facets that were ankylosed were graded as Grade 3. Each specimen was examined bilaterally at levels from C2-C3 through C6-C7, yielding 4,650 specimen assessments. The data were analyzed to compare cervical levels, gender, facet side, age groups, and race.

In the entire population of 465 specimens, the upper cervical specimens appeared to be affected by facet arthrosis more frequently than the lower levels; 12.37% of the specimens had bony evidence of arthrosis at the C2-C3 level; 13.33% of the specimens had arthrosis occur at the C3-C4 level; 14.62% at the C4-C5 level; 7.85% at the C5-C6 level, and 4.84% at the C6-C7 level. The large majority of all cervical facet arthrosis was found to be Grade 1 at all levels.

In the older population, the prevalence of facet arthrosis is as high as 29.87% for the C4-C5 level. C4-C5 level appears to be affected the most frequently, followed by the C3-C4 level, then C2-C3, C5-C6, and C6-C7.

The prevalence of cervical facet arthrosis increases with age, and occurs more commonly in the upper cervical spine.

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May 30, 2009

Head eye coordination in whiplash neck injury

Filed under: Neck Pain, Whiplash — Administrator @ 7:06 pm

Head eye coordination using simultaneous measurement of eye in head and head in space movements: potential for use in subjects with a whiplash injury

From: J Clin Monit Comput. 2009 Feb;23(1):31-40. Epub 2009 Feb 7

Sudden acceleration and deceleration forces acting on the head, such as during a motor vehicle collision, may cause neck injuries with soft tissue damage as a result. Such injuries are defined by the Quebec Task Force as whiplash associated disorders. The primary symptoms are neck pain and restricted neck movement. Dizziness and complaints of blurred vision or difficulty reading occur in some patients. Difficulty with driving, an important functional task, is common and might also be related to altered visual control.

The article published in the Journal of Clinical Monitoring and Computing describes reproducibility of a measurement method to investigate deficits in eye head coordination. Combined recordings of head and eye rotation using wireless motion sensors and electro-oculography were used as an initial step towards a method to quantify eye head coordination deficits. Head rotation to the side during gaze fixation and sequential head and eye movements were studied on 20 asymptomatic control subjects and six subjects with chronic whiplash disorders. All included whiplash subjects reported eye disturbances according to a vision symptom questionnaire.

The trial-to-trial reproducibility was moderate to high for 24 of 28 variables. Velocity gain (ratio of eye and head velocities) was on average close to unity in both groups. Head stability was high in control subjects, while three of six whiplash subjects demonstrated head instability during eye movement. Whiplash subjects also demonstrated a decreased range of head movement during gaze fixation and lower head velocities as compared with the asymptomatics.

The method of combined head and eye motion appears to give accurate, repeatable measurements. Case studies of whiplash subjects indicated deficits in head eye coordination. The method could be useful in further clinical research into eye and head movement in those with neck disorders.

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May 26, 2009

Manual Therapy, Exercise, and Traction in Cervical Radiculopathy

Filed under: Neck Pain — Administrator @ 5:52 pm

Manual Therapy, Exercise, and Traction for Patients With Cervical Radiculopathy: A Randomized Clinical Trial

From: Phys Ther. 2009 May 21. [Epub ahead of print]

Optimal strategies for the management of patients with cervical radiculopathy remain elusive. Preliminary evidence suggests that a multimodal treatment program consisting of manual therapy, exercise, and cervical traction may result in positive outcomes for patients with cervical radiculopathy. However, limited evidence exists to support the use of mechanical cervical traction in patients with cervical radiculopathy. The purpose of this study was to examine the effects of manual therapy and exercise, with or without the addition of cervical traction, on pain, function, and disability in patients with cervical radiculopathy. Design This study was a multicenter randomized clinical trial. Setting The study was conducted in orthopedic physical therapy clinics. Patients Patients diagnosed with cervical radiculopathy (N=81) were randomly assigned to 1 of 2 groups: a group that received manual therapy, exercise, and intermittent cervical traction and a group that received manual therapy, exercise, and sham intermittent cervical traction. Intervention Patients were treated, on average, 2 times per week for an average of 4.2 weeks. Measurements Outcome measurements were collected at baseline and at 2 weeks and 4 weeks using the Numeric Pain Rating Scale, the Patient-Specific Functional Scale, and the Neck Disability Index.

There were no significant differences between the groups for any of the primary or secondary outcome measures at 2 weeks or 4 weeks. The effect size between groups for each of the primary outcomes was small. Limitations were the use of a nonvalidated clinical prediction rule to diagnose cervical radiculopathy and the lack of a control group without treatment. The results suggest that the addition of mechanical cervical traction to a multimodal treatment program of manual therapy and exercise yields no significant additional benefit to pain, function, or disability in patients with cervical radiculopathy.

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May 23, 2009

Assessment of F-16 pilots and neck pain

Filed under: Neck Pain — Administrator @ 9:20 am

Functional assessment of the cervical spine in F-16 pilots with and without neck pain

From: Aviat Space Environ Med. 2009 May;80(5):477-81

Spinal symptoms in fighter pilots are a serious aeromedical problem. The most common neck complaints are muscular pain and strain. The aim of the current study was to determine possible differences in the cervical range of motion, neck position sense, and neck muscle strength between pilots with and without neck pain. There were 90 male F-16 pilots who volunteered, of which 17 had experienced bilateral neck pain. A standardized questionnaire was used to collect personal information. The maximum isometric neck flexion/extension and lateral flexion strength, the neck position sense, and the cervical range of motion were measured.

There were no significant differences between healthy pilots and those with neck pain concerning neck muscle strength and neck position sense. The neck pain group had a limited cervical range of motion in the sagittal plane and in the transversal plane compared to the healthy pilots. In the current study the authors screened for different motor skills so that deficits could be detected and retraining programs could be implemented when necessary. According to their results, individual retraining programs might reduce neck pain and therefore a well-instructed training program to maintain a proper active cervical range of motion should be implemented. Future studies should investigate the effectiveness of this kind of program.

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May 21, 2009

Relation between spinal pain and temporomandibular disorders

Filed under: Back Pain, Neck Pain, Shoulder Pain, TMJ Pain — Administrator @ 9:48 am

Does a dose-response relation exist between spinal pain and temporomandibular disorders?

From: BMC Musculoskelet Disord. 2009 Mar 2;10:28

Temporomandibular disorders are musculoskeletal pain conditions characterised by pain and dysfunction in the jaw-face muscles and/or the temporomandibular joint. Musculoskeletal pain conditions occurring at various locations may share pathophysiological mechanisms. Co-morbidity between temporomandibular disorders, headaches and neck/shoulder pain has been reported in temporomandibular disorders patient samples as well as in samples drawn from the general population. Low back pain, one of the most common pain conditions in humans, has been associated with other pains such as neck pain and headaches, which has been interpreted as a tendency for symptoms to cluster in some individuals. The source of these patterns is not known, but neurobiological sensitization processes, genetically determined vulnerability and psychological factors are commonly given as possible explanations. Results of a 3-year prospective study showed a significantly increased risk of developing a new pain condition with presence of a pain condition at baseline. A more recent prospective study based on patients with non-painful temporomandibular disorders indicated a dose-response relationship between the number of pain sites at baseline (head, back, chest, stomach) and the risk of onset of dysfunctional temporomandibular disorders pain among women. Frequency of headaches was found to have a dose-response relationship with occurrence of musculoskeletal symptoms (e.g. pain in neck, shoulders and low back) in a Norwegian population.

The authors have recently shown that patients with long-term spinal pain (neck, shoulder and/or low back) significantly more often have signs and symptoms of temporomandibular disorders than do matched controls. The associations remained statistically significant also after exclusion of those who reported jaw pain. It is not known whether co-morbidity between temporomandibular disorders and neck pain, shoulder pain and/or low back pain occurs within the whole range of variation in symptom frequency and severity. Most analyses in this field have involved dichotomized samples, not taking variations of symptom severity into consideration. The aim of the present study was to test whether a reciprocal dose-response relation exists between frequency and severity of neck pain, shoulder pain and/or low back pain and temporomandibular disorders. The authors tested the following null hypotheses:

1. Occurrence of frequent temporomandibular disorders symptoms and headaches does not differ significantly between study groups with varying frequency and severity of neck pain, shoulder pain and/or low back pain.

2. Presence of frequent neck pain, shoulder pain and/or low back pain does not differ significantly between study groups with varying frequency and severity of temporomandibular disorders symptoms.

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May 20, 2009

Retropharyngeal Tendinitis In Neck Pain

Filed under: Neck Pain — Administrator @ 9:10 am

Retropharyngeal Tendinitis May be More Common Than We Think: A Report on 45 Cases Seen in Danish Chiropractic Clinics

From: J Manipulative Physiol Ther. 2009 May;32(4):315-20

This study presents information from 45 cases of retropharyngeal tendinitis that were collected in Danish chiropractic clinics. A practicing Danish chiropractor collected cases of retropharyngeal tendinitis from colleagues who were members of the Danish Society of Chiropractic and Clinical Biomechanics. Only cases where a patient history of acute severe neck pain, cervical stiffness, and dysphagia were considered, and these were supplemented with imaging in the form of x-rays, computed tomography, or magnetic resonance imaging scans. All cases were reviewed independently by the chiropractor and a medical radiologist with a specialty in musculoskeletal disorders before acceptance into this case series.

Forty-five cases fulfilled the inclusion criteria and were included in this review. Sixteen of these were recruited from a single chiropractic practice. Nineteen were males and 26 were females with an average age of 48 years. All but 2 patients had the characteristic depositions of calcium hydroxyapatite in the tendon of the longus colli muscle, and the average diameter of the retropharyngeal space was 8.1 mm. Patients presenting with a triad of acute severe neck pan, stiff neck, and dysphagia may have retropharyngeal tendinitis. This condition may be a more common than previously thought among patients presenting with acute neck pain in the primary health care sector.

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May 19, 2009

A Challenge for Neck Pain Treatment

Filed under: Neck Pain — Administrator @ 9:18 am

Knowledge to Action: A Challenge for Neck Pain Treatment

From: J Orthop Sports Phys Ther. 2009 May;39(5):351-63

Neck pain causes significant impairment, second only to low back pain. In a recent best-evidence synthesis, the 12-month prevalence of neck pain varied from 30% to 50%, lifetime prevalence was approximately 70%, point prevalence was 22%, and the estimated incidence was 213 per 1000 person years. Sedentary lifestyles are contributing to the prevalence of neck pain. Occupational factors play a large role in the development of neck pain as one of the most frequent causes of long-term sickness absence. Some 25% of visits to chiropractors, 15% to hospital-based physiotherapists, 2% to family physicians, and 75% of musculoskeletal disease seen by rheumatologists relate to neck pain. Combined, low back pain and neck pain have cost an estimated $90 billion per year in the United States, a figure roughly equivalent to 1% of the 2004 gross domestic product. Given the burden of neck disorders for society and individuals, it is important to maximize effective strategies to treat and prevent neck pain. Equally important is for health providers to make evidence-based treatment decisions to optimize their delivery of care. There is a wide spectrum of treatments available to people with neck pain, not all of which are equally effective.

Systematic reviews can enhance incorporation into practice of the large volumes of information emerging from research on effectiveness and risks. But the authors believe that these reviews are most useful with simplified tools to facilitate translation of this knowledge into practice. They provide a “Neck Care Tool Kit” that gives a diagrammatic approach to prioritizing intervention. The evidence from a series of 11 systematic reviews by the Cervical Overview Group is depicted in decision flow-charts and tables to enhance clinical interpretation of the overview findings. On simple visual inspection of symbols in a table, the reader can establish where there is evidence of benefit or no benefit, the strength of the recommendation, and if these data represent short or long term findings. Where possible, they guide clinicians to dosage of specific neck pain treatment methods. There is no consensus as to which outcome measures to prioritize among the large number in use. This clinical commentary guides clinicians to view the evidence in enough detail to integrate it into their clinical practice environment. They conclude by delineating research gaps and proposing future research directions for neck pain treatment.

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May 13, 2009

Connective tissue growth factor in painful disc fibrosis and degeneration

Filed under: Back Pain, Disc Problems — Administrator @ 10:37 am

Expression and role of connective tissue growth factor in painful disc fibrosis and degeneration

From: Spine. 2009 Mar 1;34(5):E178-82

Low back pain is a common clinical symptom, which will affect majority of the population at some time during the course of their lives. Although the causes of the low back pain remain unclear at present, theoretically, each structural component of the lumbar spine that is innervated, such as the vertebrae, intervertebral discs, facet joints, muscles and ligaments, may be the origin of low back pain. The degree of disc degeneration and the incidence of low back pain increase in parallel with age, suggesting that disc degeneration may be the main cause of low back pain. However, disc degeneration is common in patients without low back pain, particularly in those aged older than 50 years. Disc degeneration usually appears in magnetic resonance imaging (MRI) T2-weighted images as a decline in signal intensity, i.e., the so-called black disc. Both a normal aging disc and a pathologically painful disc appear as an area of decreased signal intensity on T2-weighted images. MRI cannot differentiate between these 2 disease entities. Many studies have reported regarding the histologic changes and the possible mechanisms underlying normal age-related disc degeneration. However, the main histologic changes and the exact molecular mechanisms underlying the painful pathologic disc remain unknown.

Recent researches have shown that connective tissue growth factor is the downstream effector mediated by transforming growth factor-β1 (TGF-β1), and is closely associated with the regulation of cell proliferation and differentiation and the fibrosis of tissues and organs, and can induce the in vivo expression of the gene involved with fibroblast extracellular matrix composition. This article reports the histologic findings of surgically excised specimens from patients with discogenic low back pain and studies the connective tissue growth factor expression and distribution in the disc, using immunohistochemical staining, with the aim of investigating the histologic characteristics of the painful pathologic disc, and exploring the role of connective tissue growth factor in painful disc degeneration.

Connective tissue growth factor was first discovered in a conditioned culture medium of human umbilical vein endothelial cells. It is a secreting peptide encoded by immediate early genes. Connective tissue growth factor is synthesized and secreted by fibroblasts, smooth muscle cells, and endothelial cells. Many studies have proved that connective tissue growth factor, the putative downstream efficient response element of TGF-β1, only mediates a part of the biologic effects of TGF-β1, i.e., stimulation of fibroblast proliferation, and promotion of tissue and organ fibrosis. These effects have been confirmed in studies regarding a variety of fibrosis diseases such as renal fibrosis and liver cirrhosis. Connective tissue growth factor promotes the proliferation and activation of fibroblasts. It stimulates the synthesis of Type I and III collagen via the respondent elements of the precollagen α2 gene. Further, it is involved in the production and accumulation of extracellular matrices. Because of these, it promotes the occurrence and development of fibrosis diseases.

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May 12, 2009

Magnetic resonance imaging predicts discogenic low back pain

Filed under: Back Pain, Disc Problems — Administrator @ 7:20 pm

Can magnetic resonance imaging accurately predict concordant pain provocation during provocative disc injection?

From: Skeletal Radiol. 2009 May 9. [Epub ahead of print]

To correlate magnetic resonance image findings with pain response by provocation discography in patients with discogenic low back pain, with an emphasis on the combination analysis of a high intensity zone and disc contour abnormalities. Sixty-two patients (aged 17-68 years) with axial low back pain that was likely to be disc related underwent lumbar discography (178 discs tested). The magnetic resonance images were evaluated for disc degeneration, disc contour abnormalities, high intensity zone, and endplate abnormalities. Based on the combination of an high intensity zone and disc contour abnormalities, four classes were determined: (1) normal or bulging disc without high intensity zone; (2) normal or bulging disc with high intensity zone; (3) disc protrusion without high intensity zone; (4) disc protrusion with high intensity zone. These magnetic resonance image findings and a new combined magnetic resonance classification were analyzed in the base of concordant pain determined by discography.

Disc protrusion with high intensity zone correlated significantly with concordant pain provocation. A normal or bulging disc with high intensity zone was not associated with reproduction of pain. Disc degeneration, disc protrusion, and high intensity zone were not helpful in the identification of a disc with concordant pain. The proposed magnetic resonance classification is useful to predict a disc with concordant pain. Disc protrusion with high intensity zone on magnetic resonance imaging predicted positive discography in patients with discogenic low back pain.

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May 8, 2009

Head repositioning measurement in whiplash disorders

Filed under: Neck Pain, Whiplash — Administrator @ 10:06 am

Head repositioning accuracy to neutral: a comparative study of error calculation

From: Man Ther. 2009 Feb;14(1):110-4. Epub 2008 May 27

Deficits in cervical proprioception have been identified in subjects with neck pain through the measure of head repositioning accuracy. Nevertheless there appears to be no general consensus regarding the construct of measurement of error used for calculating head repositioning accuracy. This study investigated four different mathematical methods of measurement of error to determine if there were any differences in their ability to discriminate between a control group and subjects with a whiplash associated disorder. The four methods for measuring cervical joint position error were calculated using a previous data set consisting of 50 subjects with whiplash complaining of dizziness (whiplash associated disorder D), 50 subjects with whiplash not complaining of dizziness (whiplash associated disorder ND) and 50 control subjects.

The results indicated that no one measure of head repositioning accuracy uniquely detected or defined the differences between the whiplash and control groups. Constant error was significantly different between the whiplash and control groups from extension. Absolute errors and root mean square errors demonstrated differences between the two whiplash associated disorder groups in rotation trials. No differences were seen with variable error. The results suggest that a combination of absolute errors (or root mean square errors) and constant error are probably the most suitable measures for analysis of head repositioning accuracy.

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